NCBI Conserved Domain Search
New Search PubMed Nucleotide Protein Structure CDD Taxonomy Help?

RPS-BLAST 2.2.6 [Apr-09-2003] Query= local sequence: (261 letters) Database: cdd.v1.65 18,039 PSSMs; 5,506,404 total columns
gnl|CDD|16868 pfam01001, HCV_NS4b, Hepatitis C virus non-structural protein NS4b. No precise function has been assigned to NS4b. However, it is known that NS4b interacts with NS4a and NS3 to form a large replicase complex to direct the viral RNA replication
 Domain Relatives
PSSMs producing significant alignments: Score
(bits)
E
value
 
gnl|CDD|16868 pfam01001, HCV_NS4b, Hepatitis C virus non-structural protein ... 178 1e-45


gnl|CDD|16868, pfam01001, HCV_NS4b, Hepatitis C virus non-structural protein NS4b. No precise function has been assigned to NS4b. However, it is known that NS4b interacts with NS4a and NS3 to form a large replicase complex to direct the viral RNA replication.
             CD-Length = 192 residues, 100.0% aligned
             Score =  178 bits (452), Expect = 1e-45
Query:  17   FKQKAIGLLQTATKQAEAAAPVVESKWRTLEAFWAKHMWNFISGIQYLAGLSTLPGNPAI  76
Sbjct:  1    FAFKALGLLPPAGDQAESATPTLASLDTKFEQFWAKHMWNFRSGIQYLAGLYTLPRNPPL  60

Query:  77   ASLMAFTASITSPLTTQHTLLFNILGGWVAAQLAPPSAASAFVGAGIAGAAVGSIGLGKV  136
Sbjct:  61   AVAASFLAGLTSPLPTHVRLALALLGGWGATQLGTPSGGLAFVGAGFAGAAVGSIWLGRI  120

Query:  137  LVDILAGYGAGVAGALVAFKVMSGEMPSTEDLVNLLPAILSPGALVVGVVCAAILRRHVG  196
Sbjct:  121  LVDVLGGYEAAVSAASLTFKIMSGELPTAEDLWNLVPCLLSPGAGVVGVALAALLRSHK-  179

Query:  197  PGEGAVQWMNRLIA  210
Sbjct:  180  -GEGAVQWMNRLLT  192