A. Substance X does not alter CDK4 levels in the immunocomplex but reduces its kinase activity. False CDK4 kinase activity is not affected by exposure to sbstance X.
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B. Substance X does not affect CDK2 or CDK4 levels in the respective immunocomplexes. True

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C. Substance X reduces the kinase activity of the CDK2 containing immunocomplex at t=8-16. True

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D. CDK2 kinase activity in control cells is lower at t=0-8 than at t=8-16. False You cannot compare the kinase activity at t=8 to that of t=16, because all assays are performed on cells that were harvested at t=16.

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